Sef Peeters developed visual arts at various academies in Tilburg, Amsterdam, Krefeld (DE) and Maastricht (1965-1973) and then studied in Breda. As early as 1976, the importance of his work was recognized by the initiators of the legendary art initiative De Appel in Amsterdam. Not much later (1978-79), Bureau Buitenland invited Peeters for a traveling group exhibition Personal Worlds, including work by Bas Jan Ader, Pieter Laurens Mol and Moniek Toebosch.
This was followed by exhibitions at home and abroad. His work is represented in the collections of the Centraal Museum (Utrecht), Museum Boijmans Van Beuningen (Rotterdam), Stedelijk Museum Breda, Noord Brabants Museum (‘s-Hertogenbosch) and Zentrum für Künstlerpublikationen Bremen (DE). The exhibition at Stedelijk Museum Breda in 2020 is the last major project in which the artist himself was closely involved.
Language is an important tool for Sef Peeters. His often conceptual works are playful and deadly serious at the same time.